Authors
- Pulatova Lola Tairkhanovna Doctor of Technical Sciences
- Kurbanova Nodira Navruzovna Candidate of Biological Sciences, Assistant Professor
Annotation
The paperexplores the possibility of applying HPLC-MS methods for the identification of cephalosporin antibiotics during routine analyses with the aim of detecting
adulterated preparations of this group. To obtain additional information on the chemical structure by selecting the mass detector, the authors investigated the possibility of fragmentation of molecular ions of different generations of cephalosporin antibiotics. Carried out in optimal conditions for HPLC with mass spectrometric detection, the studypresents the results of development of a standardized methodology for qualitative and quantitative analysis of cefazolin and cefuroxime using standard samples.
How to link insert
Pulatova, L. T. & Kurbanova, N. N. (2024). PRACTICAL APPLICATION OF CHROMATOGRAPHIC METHODS IN ANALYZING THE IDENTIFICATION OF CEPHALOSPORIN ANTIBIOTICS Bulletin of the Moscow City Pedagogical University. Series "Pedagogy and Psychology", № 1 (53), 22. https://doi.org/10.25688/2076-9091.2024.53.1.02
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